Exosomes vs. Stem Cells: Understanding Advanced Regenerative Medicine in Colombia
Last medical review: January 2026 · Read time: 5 min
Important Notice: This content is for informational purposes only and does not substitute individual medical assessment. Results may vary. Always consult with the medical team before starting any treatment.
When chronic pain or a degenerative condition affects your quality of life, it is natural to look for answers beyond conventional medicine. One of the most frequent questions our specialists answer is: "What is the difference between stem cells and exosomes? Which option is right for me?".
At Regencord, we want to offer you clarity on these evidence-based regenerative medicine options available in Colombia, explaining their mechanisms, differences, and how our quality standards ensure your safety.
What are Mesenchymal Stem Cells (UC-MSC)?
Mesenchymal Stem Cells (MSCs) are multipotent stromal cells characterized by their ability to self-renew and differentiate. At Regencord, we specifically use those derived from the umbilical cord (UC-MSC).
Scientifically, they are considered a very promising therapeutic source due to their potent paracrine function (releasing beneficial molecules) and because they act as "universal donors," meaning they do not generate immune rejection. They are frequently indicated to support regeneration in damaged organs and tissues, as well as to manage severe wear in joints.
Exosomes: The "Second Generation" of Therapy
Exosomes, technically known as extracellular vesicles (EVs), are considered the "second generation" of regenerative medicine. They are not living cells, but nanovesicles (between 30 and 120 nm) that transport lipids, proteins, and nucleic acids.
Their main advantage lies in their tiny size, which allows them to cross complex biological barriers, such as the blood-brain barrier. For this reason, they have high potential for therapies targeting the brain and spinal cord, helping to modulate neuroinflammation.
Key Differences and Clinical Applications
Although both therapies seek to support recovery processes, the choice depends on the Medical Board's assessment. Some key differences include:
- Immunogenicity: As they are not cells, exosomes have very low immunogenicity, easily escaping detection by the immune system.
- Stability: Exosomes are stable particles that maintain their biological activity for prolonged periods.
- Aesthetic Uses: Due to their ability to increase collagen production and facilitate angiogenesis, they are widely investigated for beauty treatments and skin recovery.
Quality Guarantee: ISO Standards
Safety is the pillar of our practice. Regencord complies with strict international standards to ensure that each concentrate is safe, sterile, and viable. We operate under the following certifications:
- ISO 9001: Quality management system for obtaining cellular concentrates.
- ISO 13022: Risk management for medical products containing viable human cells.
- ISO 14644: Air cleanliness classification in cleanrooms (laboratory).
In addition, we perform rigorous identity controls via flow cytometry and sterility tests on all our batches.
References
- International Society for Cell & Gene Therapy (ISCT). Membership and cell therapy standards.
- Regencord Laboratories. ISO 9001, 13022, 14644 certifications and quality control processes.
- Studies on the therapeutic potential of mesenchymal cells and extracellular vesicles (Regencord Scientific Booklet).
Frequently Asked Questions
Are the treatments safe?
Yes. Clinical evidence indicates that the use of UC-MSCs and exosomes is safe and well-tolerated. At Regencord, we ensure safety through compliance with ISO standards and viability and sterility controls.
How much do the therapies cost?
Prices are referential, and the final value depends on the protocol (dosage and route) defined after the medical assessment. For international patients, stem cell therapies typically start at approximately $4,000 USD, subject to medical confirmation. We never provide final quotes without evaluating the case.
Do they help with aging?
Yes. Regenerative medicine addresses cellular mechanisms of aging and frailty. Studies have shown efficacy in improving quality of life in conditions of senile frailty.
Where are you located?
Our main headquarters is in Pereira (Coffee Axis), Colombia. We also have agreements for care in Bogotá and Barranquilla. The process always starts virtually.
Take the next step towards your well-being
Every patient is unique. Let our medical team evaluate your case to determine if you are a candidate for stem cell or exosome therapies.
